Updating jcm 145


Non-sorbitol-fermenting STEC (NSF) O157: H7 was the first STEC serotype that was isolated in association with HUS and has been the most frequently reported cause of diarrhea-associated HUS (3).However, STEC strains of other serogroups like O26, O103, O111, O121, and O145 have also been recognized to cause severe disease and outbreaks (4, 5).STEC strains were isolated from 138 (1.09%) of 12,651 patients tested.STEC strains of serogroups O26, O103, O121, O145, and O157 were the most frequent.The age of the patient (≤5 years) and the genes (STEC) was recognized as a cause of bloody diarrhea and hemolytic uremic syndrome (HUS) for the first time in two independent studies in 1982 (1, 2).Later this pathogen was found to be the main cause of diarrhea-associated HUS with a high number of cases worldwide.These serogroups, except non-sorbitol-fermenting O157, were also the most frequent among the 11 patients (all ≤5 years old) who developed HUS.


(STEC) is a heterogeneous group of bacteria causing disease ranging from asymptomatic carriage and mild infection to hemolytic uremic syndrome (HUS).

Here, we describe patients with STEC infection and characterize the STEC strains detected in our laboratory by use of PCR for from 1996 through 2011.



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