The typical features are small grouped itchy blisters, often on red plaques, situated on the back of the elbows and forearms, buttocks and front of the knees.
Although these are the common sites the rash may in addition, occur anywhere on the body including face, scalp and trunk.
The eruption is extremely itchy and may keep patients awake at night.
DH may be present at any age but most commonly begins between the ages of 15-40.
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This was confirmed by showing the enteropathy cleared with gluten withdrawal from the diet and recurred when gluten was reintroduced.
It is slightly more common in men than females at a ratio of 3:2.DH is a persistent condition and only approximately 10% of patients have a spontaneous permanent remission.It is a rare disease in the UK with the incidence being approximately ,000.The first suggestion that patients with DH also have an enteropathy identical to coeliac disease (CD) was made in 1967.
Dermatitis herpetiformis (DH) was first described as a distinct clinical entity in 1884 by an American dermatologist, Louis Duhring.The name was descriptive, dermatitis being inflammation of the skin and herpetiformis meaning group.